6xHis-TRAIL

Product information

334,95 $US

Description

Description

TRAIL (TNF-related apoptosis-inducing ligand) is a cytokine that is produced and secreted by most normal tissue cells. TRAIL binds to cell surface death receptors DR4 and DR5, by which it activates caspase-8 to induce apoptosis of cancer cells but not of normal cells. This product contains the extracellular domain (amino acids 95-281) of full-length human TRAIL and it is competent for binding of DR4 and DR5. This product has been tested for inducing apoptosis of TRAIL-sensitive cancer cell lines at concentrations of 1-50 ng/mL.

Aperçu

Aperçu

20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol, Souce: E. coli recombinant, Buffer: 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol

Additional details

Downloads

Téléchargements

http://www.ubpbio.com/temp/U1100_6xHis-TRAIL_Datasheet.pdf

Référence

UBP-U1100

Numéro de pièce fabricant

U1100

Spécification

Human

Unité de mesure

50 µg