GST-NEMO (L329P)

Product information

$450.45

Description

Description

NF-κB essential modulator (NEMO) is a regulatory subunit within IκB kinase (IKK). IKK is also composed of two unrelated catalytic subunits called IKKα and IKKβ. NEMO is additionally referred to as IKKγ, IKKAP1, or FIP-3. IKK is responsible for activating the transcription factor, NF-κB, which is involved in immune response. NEMO prefers to bind K63-linked or linear polyubiquitin chains. The L329P substitution abolishes NEMO interacts with linear polyUb chains and long K63 polyubiquitin chains.

Overview

Overview

20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol, Souce: E. coli recombinant, Buffer: 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol

Additional details

Downloads

Downloads

http://www.ubpbio.com/temp/I1510%20I1511_GST-NEMO%20(L329P)_Datasheet.pdf

SKU

UBP-I1511

Manufacturer Part Number

I1511

Specification

Human

UOM

100 µg