SBI-0206965

Product information

$277.20

Description

Description

SBI-0206965 is a potent inhibitor of the autophagy kinase ULK1. It inhibits ULK1 and ULK2 kinases with IC₅₀ of 108 nM and 711 nM, respectively. ULK1 is a serine/threonine kinase acting upsteam of PI3K to regulate the formation of autophagophores, the precursors of autophagosomes, in response to nutrient deprivation. SBI-0206965 suppresses ULK1-mediated phosphorylation events in cells, regulating autophagy and cell survival.

Overview

Overview

Powder; no buffer, Souce: chemical synthesis, Buffer: Powder; no buffer

Additional details

Downloads

Downloads

http://www.ubpbio.com/temp/F6210%20F6211_SBI-0206965_Datasheet.pdf

SKU

UBP-F6211

Manufacturer Part Number

F6211

UOM

25 mg