CAL-101(IDELALISIB, GS-1101)
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$50.00
Description
Description
CAL-101 (idelalisib or GS-1101) is a potent inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinase (PI3K) with IC50 of 2.5 nM in cell-free assays. CAL-101 decreases pAktS473, pAktT308, and the downstream target S6 in SU-DHL-5, KARPAS-422 and CCRF-SB cells with EC50 of 0.1 to 1.0 μM.
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