PR-619

Product information

$75.10

Description

Description

A cell-permeable pan deubiquitinating enzyme inhibitor that is known to inhibit ATXN3, BAP1, JOSD2, OTUD5, UCH-L1, UCH-L3, UCH-L5/UCH37, USP1, 2, 4, 5, 7, 8, 9X, 10, 14, 15, 16, 19, 20, 22, 24, 28, 47, 48, VCIP135, YOD1, as well as deISGylase PLpro, deNEDDylase DEN1, and deSUMOlyase SENP6. PR-619 inhibits many deubiquitinating enzymes in the 5-20µM range. Treating cells with PR-619 results in the accumulation of both ubiquitin and sumo-conjugated proteins.

Overview

Overview

Powder; no buffer, Souce: chemical synthesis, Buffer: Powder; no buffer

Additional details

Downloads

Downloads

http://www.ubpbio.com/temp/F2110%20F2111_PR-619_Datasheet.pdf

SKU

UBP-F2110

Manufacturer Part Number

F2110

UOM

5 mg