LDN-57444

Product information

$300.30

Description

Description

LDN-57444 is a potent small chemical inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1, IC50 = 0.88 μM). UCHL1 functions to generate free ubiquitin from ubiquitin precursors. Loss of UCH-L1 activity causes apoptosis due to an impaired ubiquitin-proteasome pathway. LDN-57444-induced reduction of free ubiquitin could increase spine size while decreasing spine density in hippocampal neurons. 

Overview

Overview

Powder; no buffer, Souce: chemical synthesis, Buffer: Powder; no buffer

Additional details

Downloads

Downloads

http://www.ubpbio.com/index.php/product/proteasome-deubiquitinase-inhibitors/ldn57444-1872.html

SKU

UBP-F2104-25

Manufacturer Part Number

F2104-25

UOM

25 mg