6xHis-Ubiquitin (K48 only)

Product information

$150.15

Description

Description

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be conjugated on proteins as monoUb or polyUb chains. Protein ubiquitination plays both proteolytic and nonproteolytic functions. Usually, polyubiquitinated proteins are targeted to the 26S proteasome for proteolysis. Typical concentration to support in vitro ubiquitination is 50-100 µM. In Ub(K48 only), all lysine residues but lysine 48 were substituted with arginines, thereby it only supports the formation of lysine 48-linked polyubiquitin chains.

Overview

Overview

20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol, Souce: E. coli recombinant, Buffer: 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol

Additional details

Downloads

Downloads

http://www.ubpbio.com/temp/E1870_6xHis-Ubiquitin%20(K48%20only)_Datasheet.pdf

SKU

UBP-E1870

Manufacturer Part Number

E1870

Specification

Human

UOM

1 mg