6xHis-Ubiquitin (K11 only)

Product information

$150.15

Description

Description

Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be conjugated on proteins as monoUb or polyUb chains. Protein ubiquitination plays both proteolytic and nonproteolytic functions. Usually, polyubiquitinated proteins are targeted to the 26S proteasome for proteolysis. Typical concentration to support in vitro ubiquitination is 50-100 µM. In Ub(K11 only), all lysine residues but lysine 11 were substituted with arginines, thereby it only supports the formation of lysine 11-linked polyubiquitin chains.

Overview

Overview

20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol, Souce: E. coli recombinant, Buffer: 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol

Additional details

Downloads

Downloads

http://www.ubpbio.com/temp/E1830_6xHis-Ubiquitin%20(K11%20only)_Datasheet.pdf

SKU

UBP-E1830

Manufacturer Part Number

E1830

Specification

Human

UOM

1 mg