6xHis-Ube2T

Product information

$150.15

Description

Description

Ube2T is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Ube2T interacts with the E3 ligase called Fanconi anemia complementation group L (FANCL) that is part of a larger complex to regulate DNA damage repair. Once FANCL interacts with Ube2T, the complex is then able to monoubiquitinate FANCD2 that leads to the DNA repair. Ube2T can also interact with the BRCA1/BARD1 complex.

Overview

Overview

20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol, Souce: E. coli recombinant, Buffer: 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol

Additional details

Downloads

Downloads

http://www.ubpbio.com/temp/C3800,C3801_6xHis-Ube2T_Datasheet.pdf

SKU

UBP-C3800

Manufacturer Part Number

C3800

Specification

Human

UOM

25 µg