6xHis-Ube2G2

Product information

$150.15

Description

Description

Ube2G2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It has been shown to complex with the E3 ligase called GP78 to catalyze K48 – linked Ub chains. This is an endoplasmic reticulum (ER) associated system to help degrade misfolded ER proteins. Ube2G2 likely interacts with Parkin (an E3 ligase that causes autosomal recessive juvenile Parkinsonism) to ubiquitinate and degrade insoluble Pael receptors.

Overview

Overview

20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol, Souce: E. coli recombinant, Buffer: 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol

Additional details

Downloads

Downloads

http://www.ubpbio.com/temp/C2300,C2301_6xHis-Ube2G2_Datasheet.pdf

SKU

UBP-C2300

Manufacturer Part Number

C2300

Specification

Human

UOM

25 µg