6xHis-Ube2C (UbcH10 )

Product information

$438.90

Description

Description

UbcH10 (Ubc2C) is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It plays a major role in the mitosis in cell cycle by binding to the anaphase-promoting complex/cyclosome (APC/C), which causes autoubiquitination and degradation of UbcH10. This in turn stabilizes cyclin A, promoting cells enter into S phase. UbcH10 also promotes ubiquitination of many substrates of APC/C.

Overview

Overview

20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol, Souce: E. coli recombinant, Buffer: 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol

Additional details

Downloads

Downloads

http://www.ubpbio.com/temp/C1300,C1301_6xHis-Ube2C%20(UbcH10%20)_Datasheet.pdf

SKU

UBP-C1301

Manufacturer Part Number

C1301

Specification

Human

UOM

100 µg